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Then store and dispose of according to local regulations. Addresses for mail and hand delivery of objections and hearing requests are provided in 40 CFR 178.25(b). The Public Inspection page This action modifies existing tolerances under FFDCA section 408(d) in response to a petition submitted to the Agency. It is interesting to note that the Palisade treatment increased grain yield at Perkins in 2013 even though the plots lodged at comparable levels as the non treated check. DER - Trinexapac-ethyl in Water - MRIDs 49282805 & 49282806 (pdf) (238.77 KB) Contact Us to ask a question, provide feedback, or report a problem. Because these products primarily affect cell elongation and not division, the number of new cells is only slightly reduced while their ability to elongate is significantly altered. In addition, this final rule does not impose any enforceable duty or contain any unfunded mandate as described under Title II of the Unfunded Mandates Reform Act of 1995 (UMRA) (Pub. Trinexapac-ethyl is a plant growth regulator that inhibits the formation of gibberellic acid and is used as an anti-lodging agent. that agencies use to create their documents. Although there is evidence of susceptibility in the rat and rabbit developmental studies and in the rat reproduction study, EPA's concern for these effects is low, and there are no residual uncertainties since the effects only occurred at the highest doses tested (360-1,200 mg/kg/day), for each study, and there were clearly identified NOAELs (60-593 mg/kg/day) for each fetal/offspring effect. LOAEL = 357 mg/kg/day, based on elevated serum cholesterol values in females, mucoid feces in females and bloody feces in both sexes, and minimal, focal vacuolation of the dorsal medial hippocampus and/or lateral midbrain in both sexes. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. The trinexapac-ethyl changes the size of the corn p lants, enabling new spatial arrangements. 4- (cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylic Acid Ethyl Ester. Because the acute and chronic dietary exposure estimates were based on several conservative assumptions (100% of crops treated with residues present at tolerance levels, default processing factors and screening level drinking water estimates), EPA is confident that the dietary exposure assessments do not underestimate risk to the general U.S. population and various population subgroups. Acute dietary (General population including infants and children), No appropriate endpoint for the general population including infants and children, Chronic RfD = 0.32 mg/kg/day cPAD = 0.32 mg/kg/day. Developmental rabbit study. Chronic risk. documents in the last year, by the Fish and Wildlife Service All risk estimates are below EPA's level of concern. Rinse skin with plenty of water or shower. EPA's response to these comments is discussed in Unit IV.C. Schedule for Beginning Reviews. edition of the Federal Register. The Agency understands the commenter's concerns and recognizes that some individuals believe that pesticides should be banned completely. Cumulative effects from substances with a common mechanism of toxicity. These effects in the dog study were observed only at high doses (>357 mg/kg/day) and with chronic exposure, and no associated neurological signs or other neuropathology were observed. 804(2). Determination of safety. EPA determines whether acute and chronic dietary pesticide exposures are safe by comparing aggregate exposure estimates to the aPAD and cPAD. These setups such as with a boomless nozzle require higher actual product rates. All Rights Reserved. documents in the last year, by the Federal Highway Administration Manganese and trinexapac-ethyl are compatible and seem to yield higher turf growth suppression than trinexapac-ethyl and iron. We conducted the trial at Stillwater (Irr), Perkins (Irr), and Chickasha (Non-Irr). A Rule by the Environmental Protection Agency on 03/02/2012. SEARCH. Emergency exemptions may be requested by a state or federal agency. 3. Chris Hartwiger, director, USGA Course Consulting Service chartwiger@usga.org, Steve Kammerer, Ph.D., regional director skammerer@usga.org, Addison Barden, agronomist abarden@usga.org, Information on the USGAs Course Consulting Service. Register, and does not replace the official print version or the official [FR Doc. 02/28/2023, 828 Statutory and Executive Order Reviews, https://www.federalregister.gov/d/2012-4984, MODS: Government Publishing Office metadata, http://ecfr.gpoaccess.gov/cgi/t/text/text-idx?&c=ecfr&tpl=/ecfrbrowse/Title40/40tab_02.tpl, http://www.epa.gov/pesticides/factsheets/riskassess.htm, http://www.epa.gov/oppefed1/models/water/index.htm, http://www.epa.gov/pesticides/trac/science/trac6a05.pdf, http://www.epa.gov/pesticides/cumulative, Acute dietary (Females 13-49 years of age), Acute RfD = 0.6 mg/kg/day aPAD = 0.6 mg/kg/day. This information is not part of the official Federal Register document. It is not an official legal edition of the Federal For hazards that have a threshold below which there is no appreciable risk, the toxicological POD is used as the basis for derivation of reference values for risk assessment. In this Issue, Documents Trinexapac-Ethyl C13H16O5 at Best Price in Mumbai, Maharashtra | National Analytical Corporation - Chemical Division 100 Onwards INR Get Latest Price Minimum Order Quantity : 1 Kilograms/Kilograms Molecular Weight 252.26 Grams (g) Molecular Formula C13H16O5 View more details Accepts all Domestic/Foreign inquiries Send Inquiry The Agency used screening level water exposure models in the dietary exposure analysis and risk assessment for trinexapac-ethyl in drinking water. Also, the Agency calculated dietary burden differently by using the highest residue measured in trials instead of the proposed tolerance level residues. Gibberellin is a plant hormone that promotes growth of various plant organs. Before making a final registration decision on trinexapac-ethyl and MODDUS, Health Canada's PMRA will consider any comments received from the public in response to PRD2020-13. Therefore, tolerances are established for residues of trinexapac-ethyl, including its metabolites and degradates, as set forth in the regulatory text. What are the uses of Trinexapac-ethyl ? the material on FederalRegister.gov is accurately displayed, consistent with Export Percentage. The documents posted on this site are XML renditions of published Federal Modeled estimates of drinking water concentrations were directly entered into the dietary exposure model. Please note that, to comply with Canada's . The finer the spray particle size, the more uptake and suppression you're likely to get. EPA's exposure assessments have been updated to include the additional exposure from the increased tolerance of trinexapac-ethyl from use in or on sugarcane, cane and sugarcane, molasses. As to residue levels in food, EPA assumed that residues are present in all commodities at the tolerance level and that 100% of commodities with tolerances are treated with trinexapac-ethyl. Register (ACFR) issues a regulation granting it official legal status. The following five field observations are strategies that may increase the effectiveness of trinexapac-ethyl when applying it for bermudagrass growth suppression: Use a low carrier volume. // -->, A data sheet from the Compendium of Pesticide Common Names, InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3, ethyl 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylate. The goal to is to apply trinexapac-ethyl only to the leaf as this is the only route of uptake into the plant. That document referenced a summary of the petition prepared by Syngenta Crop Protection, LLC, the registrant, which is available in the docket, http://www.regulations.gov. While application of Palisade resulted in numeric reductions in plant height at Chickasha and Stillwater in 2013, differences among treatments were not statistically significant. Also, the tolerance for sugarcane, molasses is established at a different level than requested to conform with EPA's rounding class practice by removing the trailing zero. Tolerances are established for residues of the plant growth inhibitor, trinexapac-ethyl, including its metabolites and degradates, in or on the commodities in the table below. The OFR/GPO partnership is committed to presenting accurate and reliable Lose the iron and calcium. More information and documentation can be found in our . Most requests are made by state . In 2022, the global top five. documents in the last year, 861 Trinexapac-ethyl is a plant hormone , a plant growth regulator. Objections and requests for hearings must be received on or before January 4, 2021, and must be filed in accordance with the instructions provided in 40 CFR part 178 (see also Unit I.C. documents in the last year, 121 documents in the last year, by the Federal Communications Commission Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations. Monoisotopic mass 252.099777 Da. In applying this provision, EPA either retains the default value of 10X, or uses a different additional safety factor when reliable data available to EPA support the choice of a different factor. The addition of iron and calcium does not render trinexapac-ethyl inactive, but it may decrease the activity at a given rate. on documents in the last year, 522 trinexapac-ethyl is approved for use . The documents posted on this site are XML renditions of published Federal EPA assessed residential exposure with the assumption that homeowner handlers wear shorts, short-sleeved shirts, socks, and shoes, and that they complete all tasks associated with the use of a pesticide product including mixing/loading, if needed, as well as the application. If you are worried about bronzing, tank mix a product that contains manganese rather than iron. 2. on I have served as an Assistant Professor and Small Grains Extension Specialist at Oklahoma State University since August 2019. tradeKorea is a online B2B trade website offers you matching services to connect buyers and suppliers. Application of Palisade plus Tilt reduced lodging over Palisade alone at Chickasha. 'S level of concern for mail and hand delivery of objections and hearing requests are provided in 40 CFR (... Bronzing, tank mix a product that contains manganese rather than iron Tilt. 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